{"id":3498,"date":"2025-11-12T15:39:23","date_gmt":"2025-11-12T14:39:23","guid":{"rendered":"https:\/\/proxipel.ch\/biorefineries-the-little-known-role-of-granulation-in-the-efficiency-of-extraction-processes\/"},"modified":"2026-07-14T19:07:12","modified_gmt":"2026-07-14T17:07:12","slug":"biorefineries-the-little-known-role-of-granulation-in-the-efficiency-of-extraction-processes","status":"publish","type":"post","link":"https:\/\/proxipel.ch\/en\/biorefineries-the-little-known-role-of-granulation-in-the-efficiency-of-extraction-processes\/","title":{"rendered":"Biorefineries: The Little-Known Role of Granulation in the Efficiency of Extraction Processes"},"content":{"rendered":"<div id=\"attachment_2309\" style=\"width: 2570px\" class=\"wp-caption aligncenter\"><img decoding=\"async\" aria-describedby=\"caption-attachment-2309\" class=\"wp-image-2309 size-full\" src=\"https:\/\/proxipel.ch\/wp-content\/uploads\/2025\/11\/Proxipel-labo-RD-scaled.webp\" alt=\"Granulation increases extraction yields\" width=\"2560\" height=\"1707\" srcset=\"https:\/\/proxipel.ch\/wp-content\/uploads\/2025\/11\/Proxipel-labo-RD-scaled.webp 2560w, https:\/\/proxipel.ch\/wp-content\/uploads\/2025\/11\/Proxipel-labo-RD-1280x854.webp 1280w, https:\/\/proxipel.ch\/wp-content\/uploads\/2025\/11\/Proxipel-labo-RD-980x653.webp 980w, https:\/\/proxipel.ch\/wp-content\/uploads\/2025\/11\/Proxipel-labo-RD-480x320.webp 480w\" sizes=\"(min-width: 0px) and (max-width: 480px) 480px, (min-width: 481px) and (max-width: 980px) 980px, (min-width: 981px) and (max-width: 1280px) 1280px, (min-width: 1281px) 2560px, 100vw\" \/><p id=\"caption-attachment-2309\" class=\"wp-caption-text\">Granulation increases extraction yields<\/p><\/div>\n<h2><strong>Biorefineries, a key tool in the energy transition\u2026that are hampered by their production costs:<\/strong><\/h2>\n<p style=\"text-align: justify;\">The transition to a bio-based, low-carbon economy depends on the ability to replace petrochemical resources with local, renewable biomass. However, unlike the petrochemical industry\u2014which has been highly industrialized and optimized for over a century\u2014the bio-based sector faces major challenges across the entire value chain: <\/p>\n<ul>\n<li>Collection and logistics: Biorefineries around the world consume thousands of metric tons of biomass every day (ranging from 1,800 to 4,500 metric tons per site, according to Axelos et al., 2020), a resource that is scattered, seasonal, moist, and perishable, making it difficult to ensure a continuous and consistent supply;<\/li>\n<li>Processing and yield: The complex and variable composition of biomass, its low concentration, and its moisture content affect the efficiency and viability of industrial processes;<\/li>\n<li>Adapted industrial organization: The spatial and temporal variability of raw materials requires new management strategies and customized technologies to optimize material and energy flows.<\/li>\n<\/ul>\n<p>As a result, emerging biorefineries are struggling to achieve competitiveness, reliability, and sustainability\u2014major obstacles to the growth of the bioeconomy, despite its strategic economic and environmental potential for France and Europe (SNMB, European Green Deal).<br \/>\n<!-- Encadr\u00e9 argumentaire --><\/p>\n<div style=\"display: grid; grid-template-columns: repeat(auto-fit,minmax(220px,1fr)); gap: 16px; align-items: stretch;\">\n<div style=\"padding: 16px; border: 5px solid #e5e7eb; border-radius: 12px; background: white;\">\n<h3 style=\"margin: 0px 0px 8px; font-size: 18px; line-height: 1.3; text-align: center;\"><strong>Securing Supplies<\/strong><\/h3>\n<\/div>\n<div style=\"padding: 16px; border: 5px solid #e5e7eb; border-radius: 12px; background: white;\">\n<h3 style=\"margin: 0px 0px 8px; font-size: 18px; line-height: 1.3; text-align: center;\"><strong>Process Efficiency<\/strong><\/h3>\n<\/div>\n<div style=\"padding: 16px; border: 5px solid #e5e7eb; border-radius: 12px; background: white;\">\n<h3 style=\"margin: 0px 0px 8px; font-size: 18px; line-height: 1.3; text-align: center;\"><strong>Integration &#038; Circularity<\/strong><\/h3>\n<\/div>\n<\/div>\n<h3><\/h3>\n<h3><strong>A discovery that significantly impacts extraction yields at biorefineries:  <\/strong><\/h3>\n<p>Our research, which initially focused on methods<strong>for extracting<\/strong>polyphenols from grapevine shoots, led to an unexpected discovery regarding the pretreatment of biomass.<\/p>\n<p>Beyond the well-known logistical benefits of granulation \u2014<\/p>\n<ul>\n<li>A 5-fold reduction in the volume of goods transported and stored,<\/li>\n<li>Natural stabilization of biomass through drying,<\/li>\n<li>Production of a homogeneous, dry, ready-to-use intermediate<\/li>\n<\/ul>\n<div id=\"attachment_2273\" style=\"width: 298px\" class=\"wp-caption alignright\"><img decoding=\"async\" aria-describedby=\"caption-attachment-2273\" class=\" wp-image-2273\" src=\"https:\/\/proxipel.ch\/wp-content\/uploads\/2025\/11\/extraction-300x217.png\" alt=\"Extraction of molecules of interest\" width=\"288\" height=\"208\"><p id=\"caption-attachment-2273\" class=\"wp-caption-text\"><em>Figure 1: The granulation method increases the availability of virtually all polyphenols of interest derived from grapevines, including resveratrol<\/em><\/p><\/div>\n<p>We have shown that, under certain granulation conditions, the extraction yield of the molecules of interest increases by 25 to 30 percent.<br \/>\nThis improvement is significantly greater than that achieved through heat treatment, pressure treatment, or even a combination of the two, thanks to a specific mechanical effect of granulation that breaks down the lignocellulosic matrix, ruptures the cell walls, and more effectively releases the biological components.<\/p>\n<p>&nbsp;<\/p>\n<p>The use of this technology would directly impact the efficiency of biorefineries and would enable:<\/p>\n<p><img decoding=\"async\" class=\" wp-image-2290 alignleft\" src=\"https:\/\/proxipel.ch\/wp-content\/uploads\/2025\/11\/Proxipel-05_1_11zon-300x200.webp\" alt=\"Vine shoot pellets\" width=\"258\" height=\"172\"><\/p>\n<ul>\n<li style=\"text-align: left;\">a decrease in CAPEX for the construction of new biorefineries,<\/li>\n<li>an increase in productivity at existing facilities, without additional investment<\/li>\n<li>and a major <strong>simplification<\/strong>of biomass collection and processing, from the field to the plant.<\/li>\n<\/ul>\n<p>&nbsp;<\/p>\n<p>This discovery paves the way for an integrated optimization of the bio-based supply chain that is more <strong>efficient<\/strong>, cost-effective, and sustainable, and can be applied to a wide variety of plant resources.<\/p>\n<h3><strong> <\/strong><strong>Proxipel offers the first fully integrated mobile granulation unit:  <\/strong><\/h3>\n<p>To actually deploy this technology in the field, we have developed a <a href=\"https:\/\/proxipel.ch\/en\/technology\/\" target=\"_blank\" rel=\"noopener\"><span style=\"color: #99cc00;\">mobile granulation<\/span><\/a> and drying unit capable of operating directly at biomass production sites (farms, vineyards, forests, agri-food facilities, etc.).<\/p>\n<p>This compact, self-contained unit allows you to:<\/p>\n<ul>\n<li>the immediate processing of biomass on site, without the need for prior transportation or heavy infrastructure,<\/li>\n<li>A granulation recipe specific to each type of biomass, directly integrated into the unit\u2019s PLC, that is fully repeatable without manual intervention. This allows for great <strong>versatility<\/strong>. <\/li>\n<li>a drastic reduction in the volume to be transported (up to 80% less mass),<\/li>\n<li><strong>stabilizing<\/strong>and standardizing the product before shipping it to biorefineries,<\/li>\n<li>and the production of a dry, uniform granule ready for extraction.<\/li>\n<\/ul>\n<p><img decoding=\"async\" class=\" wp-image-715 alignright\" src=\"https:\/\/proxipel.ch\/wp-content\/uploads\/2024\/10\/camion-300x153.png\" alt=\"Proxipel, the first fully integrated mobile pelletizing unit\" width=\"355\" height=\"181\">Thanks to this mobile and modular approach, it becomes possible to process scattered feedstock sources locally, thereby securing supply for biorefineries and reducing their carbon footprint.<\/p>\n<p>The mobile unit thus serves as a strategic link between biomass production and its industrial processing, combining operational efficiency, energy efficiency, and the creation of local value.<\/p>\n<h3><strong><img decoding=\"async\" class=\"size-medium wp-image-2298 alignleft\" src=\"https:\/\/proxipel.ch\/wp-content\/uploads\/2025\/11\/Proxiflex-deployee-200x300.webp\" alt=\"Proxiflex Mobile Granulation Unit\" width=\"200\" height=\"300\">We are looking for:  <\/strong><\/h3>\n<p>Proxipel, an expert in biomass granulation, is seeking strategic industrial partners active in the cosmetics, extraction, and pharmaceutical sectors who wish to leverage this discovery to:<\/p>\n<ul>\n<li>Optimize the operation of their biorefineries,<\/li>\n<li>Reduce their production costs,<\/li>\n<li>Secure their biomass supplies,<\/li>\n<li>and make the most of new local resources.<\/li>\n<\/ul>\n<p>This collaboration will enable us to quickly scale the technology to an industrial level, while generating significant operational and economic benefits for our partners. Interested? <span style=\"color: #99cc00;\"><strong><a style=\"color: #99cc00;\" href=\"https:\/\/proxipel.ch\/en\/contact\/\">Contact us<\/a><\/strong>!<\/span> <\/p>\n<p>&nbsp;<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Biorefineries, a key tool in the energy transition\u2026that are hampered by their production costs: The transition to a bio-based, low-carbon economy depends on the ability to replace petrochemical resources with local, renewable biomass. However, unlike the petrochemical industry\u2014which has been highly industrialized and optimized for over a century\u2014the bio-based sector faces major challenges across the [&hellip;]<\/p>\n","protected":false},"author":6,"featured_media":2310,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_et_pb_use_builder":"off","_et_pb_old_content":"","_et_gb_content_width":"","inline_featured_image":false,"footnotes":""},"categories":[45],"tags":[],"class_list":["post-3498","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-blog"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v28.3 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Biorefineries: The Little-Known Role of Granulation in the Efficiency of Extraction Processes - Proxipel<\/title>\n<meta name=\"description\" content=\"Reduce your costs and increase your extraction yields: discover Proxipel\u2019s mobile granulation technology.\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/proxipel.ch\/en\/biorefineries-the-little-known-role-of-granulation-in-the-efficiency-of-extraction-processes\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Biorefineries: The Little-Known Role of Granulation in the Efficiency of Extraction Processes - 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